Patient portal +48 500 015 560

Acoustic Neuromodulation Therapy of horizontal fibers. Hyperactivity of horizontal fibers.


Tinnitus causes and plasticity models: Hyperactive horizontal fibers of the auditory cortex

 

During sudden hearing loss, the nervous system is changing. The main reason is a need of having an effective source of stimulation while having a great population of neurons. After many years of living with tinnitus, one tinnitus patient can have two different models that generate it. Except enhanced synchronization, characterized by activity of neurons and inadequately connected with lesser number of cells,  we can observe plasticity emergence, called hyperactivity of horizontal fibers in the auditory cortex. Horizontal fibers of the auditory cortex are used to communicate with neurons. They make inter-neuron communication possible and automatically regulate activity level in relation to a number of acoustic objects present on the whole surface of auditory cortex. Hyperactivity of one of the neuron structures often leads to increased activity of horizontal fibers in neurons which lack damage and hyperactivity. Then, healthy stimulated neurons connect with hyperactive structure in order to discover the reason for increased activity. If situation remains unchanged, it may lead to lack of balance between hampering and excitatory neurotransmitters. Teaching healthy neurons how to communicate with each other is the only way to reduce plasticity. Due to this communication, horizontal fibers return to their initial size and tinnitus is then generated on the basis of one model.

 

Typical symptoms: a shriek changing into low-pitch and high-pitch sounds, disappearing hiss which returns within minutes

Technology of reduction

  • 74%

    Tinnitus reduction above 50 % in TQ score
  • 26%

    Tinnitus reduction below 50 % in TQ score

Effectivness of  Tinnitus Reduction in Horizontal hiperactivity  auditory cortex fibers  with out diet and physical activity in clinical research :

Tass, Adamchic, Freund, von Stackelberg, Hauptmann: Restorative Neurology and Neuroscience (2012) Acoustic neuromodulation CR in chronic tinnitus

 

63 Patients use Acoustic Neuromodulation CR  durring 10 month therapy protocol , the results was 74 % of subjects had reduced tinnitus above 50 % in TQ score 26 % had reduced tinnitus below 50 % in TQ score 

Is it possible to cure tinnitus with acoustic neuromodulation?

It’s one of the steps to reduce tinnitus. As we have already mentioned above, usually activity of horizontal fibers is additional to one of the models. Thus, in order to effectively reduce, for example, enhanced synchronization model with hyperactive fibers, first we need to reduce hyperactivity. In this case, we will use rTMS therapy.

Why research studies on effectiveness of this method don’t exist?

In the bookmark Research studies you can find research which confirm existence of this model generating tinnitus and describe this method. It’s widely used in England and Germany where CE certificate is required. Medical certificates are awarded only for therapeutic devices, consequently, testing effectiveness and positive influence of stimulation on tinnitus reduction. It informs us that it was needed for this technology to undergo clinical tests in order to evaluate influence of stimulation, and it succeeded.

Why acoustic neuromodulation is used in Germany to every tinnitus model?

We are the first clinic in the world that put into practice 4 different models generating tinnitus and four technologies that match them. In Europe, there is 6 other places where they deal with diagnostics as precisely as we do; however, they haven’t gained sufficient diagnostics and treatment yet. Certainly, in the future during international audiology conferences, we will tackle the subject of our technologies. We would like to develop this knowledge for others, but as for now, we are very much focused on the treatment process itself and tinnitus reduction, rather than on sharing it with others. However, we are open to help anyone interested in this field.

Does TRT habituation method is, to some extent, similar to acoustic neuromodulation therapy or synaptic adaptation Arc therapy?

TRT habituation therapy delevoped in times when inventor weren’t certain how tinnitus generates and how many different types it has. Thus, in theory, TRT therapy can’t have therapeutic abilities and what makes it different from current therapies is lack of aim and process to be triggered. It’s only goal is to kill the hiss. (..) research was carried out to confirm that amygdala (responsible for lessening activity of the auditory cortex in certain situations) can be susceptible to a short-term customization to a sound, for example, in silence. In this regard, one auditory cortex analyzes two signals: fast and slowly changing within time. In prehistory, monotonous noise of environment was hushed down in order for neurons of the auditory cortex, which analyze changing within time signal, to hear the sound of a breaking branch. However, the process doesn’t work in a long-term habituation of neurons. If it did work that way, the neurons would be hushed down and less susceptible to a certain frequency range. If danger appeared and information as a sound alarm, we wouldn’t be able to hear it. We can’t let that happen. Every technology we offer aims at triggering a certain process, which goal is to reduce excitement of synapses or neurons. TRT research doesn’t include a term synaptic scaling which indicates invalidity of this therapy.

Why TRT is still widely used in Poland?

The scale of using this particular technology in Poland and in the world means how little specialists and doctors know about tinnitus treatment. Doctors aren’t interested in neurobiology, or even audiology; thus, they don’t know much what’s been going on and what’s new in this field of study. Tinnitus in fact, should be called hiss of synapses in the nervous system, which indicates invalidity of terminology in relation to knowledge and research studies, not to mention types of technologies.

Technology of tinnitus reduction caused by hyperactive horizontal fibers of the auditory cortex. Acoustic neuromodulation therapy of horizontal fibers

CR acoustic neuromodulation therapy was created in Germany and patented in 2012. Ever since, it’s been used by ANM neuromodulation company in Germany and made available for many specialists in Germany and England. Our clinic has used this technology for quite a time but, due to numerous limitations and actualizations, we were forced to create our own counterpart of the CR acoustic neuromodulation therapy. Our technology stimulates a range of horizontal fibers within the whole range of human hearing from 125 Hz up to 20 kHz. In addition, it doesn’t consider algorithm in hyperactive structure but in cross-border frequency connections of horizontal fibers. We have developed this technology in terms of not using it in every case, in comparison with Germans, we are aware of differences in patients’ hyperactive structures of horizontal fibers. 

 

Thus, our technology is more effective because of qualifying patients to a stated hyperactive structure of horizontal fibers. The technology stimulates a range of neurons excessively connected with hyperactive structure which generates tinnitus. Through an alternating stimulation of those ranges, neurons start to create more connections between themselves and a stronger structure of horizontal fibers. This causes weakening and lessening of connections between properly working structure and hyperactive structure. It reduces a symptom heard by a patient as high-pitched sounds modulated by each other. Hyperactivity of a horizontal fibers structure is very often described as sharp and high-pitched sounds. Technology itself reduces hyperactivity of horizontal fibers, not the real cause of generating tinnitus. In some cases, a structure of auditory cells was reconstructed after acoustic trauma, but neurons of the auditory cortex remain hyperactive. In this sort of situation, activity of horizontal fibers is often increased and only one technology is needed to reduce tinnitus, for instance, acoustic neuromodulation therapy.

 

Hyperactive fibers reduction time: from a few days to 3-4 months. After reducing horizontal fibers, we can move to a target tinnitus reduction

The cost of therapy : 2000 Euro